RARA
Information RARA
- Description
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]
- Full Name
retinoic acid receptor alpha
- Source NCBI
ReMap Statistics
- Datasets
- 4
- Biotypes
- 4
- Peaks
- 138,110
- Non-redundant peaks
- 126,004
TF Classification
- Super Class
- Zinc-coordinating DNA-binding domains
- Class
- Nuclear receptors with C4 zinc fingers
- Familly
- Thyroid hormone receptor-related factors (NR1)
- Sub Familly
- Retinoic acid receptors (NR1B)
Source TFClass
External IDs
- JASPAR
- MA1149
- Ensembl
- ENSG00000131759
- UniProt
- P10276
- Genevisible
- P10276
- RefSeq
- NM_000964
- Aliases
- NR1B1; RAR
Datasets Table for RARA
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| RARA | Hep-G2 | ENCODE | Homo sapiens | ENCSR500WXT | 107,923 | |||
| RARA | SK-N-SH | GEO | Homo sapiens | GSE69119 | 1,841 | |||
| RARA | TSU-1621MT | GEO | Homo sapiens | GSE60477 | 25,471 | |||
| RARA | U-937 | ATRA-treated_RAR | GEO | Homo sapiens | GSE98006 | 2,875 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |