PAX8
Information PAX8
- Description
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
- Full Name
paired box 8
- Source NCBI
ReMap Statistics
- Datasets
- 9
- Biotypes
- 9
- Peaks
- 80,560
- Non-redundant peaks
- 80,248
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Paired box factors
- Familly
- Paired domain only
- Sub Familly
- PAX-2-like factors (partial homeobox)
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000125618
- UniProt
- Q06710
- Genevisible
- Q06710
- RefSeq
- NM_003466
- Aliases
Datasets Table for PAX8
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| PAX8 | GM12878 | ENCODE | Homo sapiens | ENCSR192AFN | 1,843 | |||
| PAX8 | K-562 | ENCODE | Homo sapiens | ENCSR274CGK | 2,087 | |||
| PAX8 | MCF-7 | ENCODE | Homo sapiens | ENCSR949IWY | 1,169 | |||
| PAX8 | FT194 | GEO | Homo sapiens | GSE79893 | 9 | |||
| PAX8 | FT246 | GEO | Homo sapiens | GSE79893 | 261 | |||
| PAX8 | FT33 | GEO | Homo sapiens | GSE79893 | 12 | |||
| PAX8 | JHOS4 | GEO | Homo sapiens | GSE79893 | 10 | |||
| PAX8 | Kuramochi | GEO | Homo sapiens | GSE79893 | 28 | |||
| PAX8 | OVSAHO | GEO | Homo sapiens | GSE79893 | 75,141 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |