PATZ1

Information PATZ1

Description

The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008]

Full Name

POZ/BTB and AT hook containing zinc finger 1

Source NCBI

ReMap Statistics

Datasets
2
Biotypes
1
Peaks
58,128
Non-redundant peaks
54,582

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000100105
UniProt
Q9HBE1
Genevisible
Q9HBE1
RefSeq
NM_014323
Aliases
MAZR; PATZ; RIAZ; ZBTB19; ZNF278; ZSG; dJ400N23
All peaks PATZ1
Download BED file
Non redundant peaks PATZ1
Download BED file
SEQUENCES PATZ1
Download FASTA file
DOWNLOAD All ReMap
Got to catalogue

Datasets Table for PATZ1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
PATZ1 HEK293 ENCODE Homo sapiens ENCSR966ULI 53,670
PATZ1 HEK293 GEO Homo sapiens GSE76494 4,458
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.