NFYB
Information NFYB
- Description
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]
- Full Name
nuclear transcription factor Y subunit beta
- Source NCBI
ReMap Statistics
- Datasets
- 4
- Biotypes
- 3
- Peaks
- 45,612
- Non-redundant peaks
- 24,956
TF Classification
- Super Class
- Other all-alpha-helical DNA-binding domains
- Class
- Heteromeric CCAAT-binding factors
- Familly
- Heteromeric CCAAT-binding factors
- Sub Familly
- None
Source TFClass
External IDs
- JASPAR
- MA0502
- Ensembl
- ENSG00000120837
- UniProt
- P25208
- Genevisible
- P25208
- RefSeq
- NM_006166
- Aliases
- CBF-A; CBF-B; HAP3; NF-YB
Datasets Table for NFYB
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NFYB | GM12878 | ENCODE | Homo sapiens | ENCSR000DNM | 8,893 | |||
| NFYB | K-562 | ENCODE | Homo sapiens | ENCSR000EGQ | 13,231 | |||
| NFYB | HeLa-S3 | ENCODE | Homo sapiens | ENCSR000DNR | 8,235 | |||
| NFYB | K-562 | GEO | Homo sapiens | GSE26439 | 15,253 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |