NCOR2
Information NCOR2
- Description
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]
- Full Name
nuclear receptor corepressor 2
- Source NCBI
ReMap Statistics
- Datasets
- 4
- Biotypes
- 3
- Peaks
- 64,813
- Non-redundant peaks
- 60,443
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Tryptophan cluster factors
- Familly
- Myb/SANT domain factors
- Sub Familly
- NCoR-like factors
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000196498
- UniProt
- Q9Y618
- Genevisible
- Q9Y618
- RefSeq
- NM_001077261
- Aliases
- CTG26; N-CoR2; SMAP270; SMRT; SMRTE; SMRTE-tau; TNRC14; TRAC; TRAC-1; TRAC1
Datasets Table for NCOR2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NCOR2 | LS180 | GEO | Homo sapiens | GSE39277 | 17,156 | |||
| NCOR2 | LS180 | 125 | GEO | Homo sapiens | GSE39277 | 29,423 | ||
| NCOR2 | OCI-Ly1 | GEO | Homo sapiens | GSE29282 | 7,715 | |||
| NCOR2 | B-cell | GERMINAL_CENTER | GEO | Homo sapiens | GSE43350 | 10,519 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |