NCOR1
Information NCOR1
- Description
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]
- Full Name
nuclear receptor corepressor 1
- Source NCBI
ReMap Statistics
- Datasets
- 9
- Biotypes
- 4
- Peaks
- 158,348
- Non-redundant peaks
- 124,382
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Tryptophan cluster factors
- Familly
- Myb/SANT domain factors
- Sub Familly
- NCoR-like factors
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000141027
- UniProt
- O75376
- Genevisible
- O75376
- RefSeq
- NM_001190438
- Aliases
- KIAA1047; MGC104216; N-CoR; N-CoR1; PPP1R109; TRAC1; hCIT529I10; hN-CoR
Datasets Table for NCOR1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NCOR1 | K-562 | ENCODE | Homo sapiens | ENCSR000ATY | 819 | |||
| NCOR1 | K-562 | ENCODE | Homo sapiens | ENCSR298JCG | 5,788 | |||
| NCOR1 | K-562 | ENCODE | Homo sapiens | ENCSR798ILC | 33,592 | |||
| NCOR1 | K-562 | ENCODE | Homo sapiens | ENCSR910JAI | 17,729 | |||
| NCOR1 | HEK293T | SICTR | GEO | Homo sapiens | GSE35197 | 13,124 | ||
| NCOR1 | HEK293T | SIGSP2 | GEO | Homo sapiens | GSE35197 | 1,754 | ||
| NCOR1 | LS180 | GEO | Homo sapiens | GSE39277 | 37,930 | |||
| NCOR1 | LS180 | 125 | GEO | Homo sapiens | GSE39277 | 39,101 | ||
| NCOR1 | OCI-Ly1 | GEO | Homo sapiens | GSE29282 | 8,511 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |