NCOA3
Information NCOA3
- Description
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010]
- Full Name
nuclear receptor coactivator 3
- Source NCBI
ReMap Statistics
- Datasets
- 5
- Biotypes
- 2
- Peaks
- 215,195
- Non-redundant peaks
- 195,170
TF Classification
- Super Class
- Basic domains
- Class
- Basic helix-loop-helix factors (bHLH)
- Familly
- PAS domain factors
- Sub Familly
- NCoA factors
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000124151
- UniProt
- Q9Y6Q9
- Genevisible
- Q9Y6Q9
- RefSeq
- NM_001174087
- Aliases
- ACTR; AIB-1; AIB1; CAGH16; CTG26; KAT13B; RAC3; SRC-3; SRC3; TNRC14; TNRC16; TRAM-1; bHLHe42; p/CIP; pCIP
Datasets Table for NCOA3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NCOA3 | MCF-7 | ENCODE | Homo sapiens | ENCSR573OJP | 7,053 | |||
| NCOA3 | MCF-7 | ENCODE | Homo sapiens | ENCSR686SOV | 4,418 | |||
| NCOA3 | MCF-7 | ENA | Homo sapiens | ERP000901 | 154,558 | |||
| NCOA3 | MCF-7 | E2 | ENA | Homo sapiens | ERP000901 | 46,371 | ||
| NCOA3 | H3396 | E2 | GEO | Homo sapiens | GSE32349 | 2,795 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |