NCOA1
Information NCOA1
- Description
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
- Full Name
nuclear receptor coactivator 1
- Source NCBI
ReMap Statistics
- Datasets
- 8
- Biotypes
- 4
- Peaks
- 77,281
- Non-redundant peaks
- 64,482
TF Classification
- Super Class
- Basic domains
- Class
- Basic helix-loop-helix factors (bHLH)
- Familly
- PAS domain factors
- Sub Familly
- NCoA factors
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000084676
- UniProt
- Q15788
- Genevisible
- Q15788
- RefSeq
- NM_001362950
- Aliases
- F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74
Datasets Table for NCOA1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| NCOA1 | K-562 | ENCODE | Homo sapiens | ENCSR658WFQ | 23,159 | |||
| NCOA1 | K-562 | ENCODE | Homo sapiens | ENCSR711SNW | 939 | |||
| NCOA1 | K-562 | ENCODE | Homo sapiens | ENCSR931HNY | 12,888 | |||
| NCOA1 | MCF-7 | ENA | Homo sapiens | ERP000901 | 20,525 | |||
| NCOA1 | MCF-7 | E2 | ENA | Homo sapiens | ERP000901 | 11,859 | ||
| NCOA1 | LS180 | GEO | Homo sapiens | GSE39277 | 4,772 | |||
| NCOA1 | LS180 | 125 | GEO | Homo sapiens | GSE39277 | 2,594 | ||
| NCOA1 | U2OS | E2 | GEO | Homo sapiens | GSE26110 | 545 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |