MORC2
Information MORC2
- Description
This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
- Full Name
MORC family CW-type zinc finger 2
- Source NCBI
ReMap Statistics
- Datasets
- 7
- Biotypes
- 3
- Peaks
- 52,491
- Non-redundant peaks
- 41,943
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000133422
- UniProt
- Q9Y6X9
- Genevisible
- Q9Y6X9
- RefSeq
- NM_001303256
- Aliases
- AC004542.C22.1; CMT2Z; KIAA0852; ZCW3; ZCWCC1
Datasets Table for MORC2
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MORC2 | HeLa | V5-HUSH-KO | GEO | Homo sapiens | GSE95451 | 15,627 | ||
| MORC2 | HeLa | V5-MORC2-KO | GEO | Homo sapiens | GSE95451 | 5,679 | ||
| MORC2 | HeLa | V5-MORC2-KO-W505A-MORC2-mut | GEO | Homo sapiens | GSE95451 | 12,462 | ||
| MORC2 | H9 | GEO | Homo sapiens | GSE95374 | 16,584 | |||
| MORC2 | K-562 | GEO | Homo sapiens | GSE95374 | 1,828 | |||
| MORC2 | K-562 | MPP8-KO | GEO | Homo sapiens | GSE95374 | 135 | ||
| MORC2 | K-562 | TASOR-KO | GEO | Homo sapiens | GSE95374 | 176 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |