MCM2

Information MCM2

Description

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]

Full Name

minichromosome maintenance complex component 2

Source NCBI

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
1,056
Non-redundant peaks
1,056

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000073111
UniProt
P49736
Genevisible
P49736
RefSeq
NM_004526
Aliases
BM28; CCNL1; CDCL1; D3S3194; DFNA70; KIAA0030; MITOTIN; cdc19
All peaks MCM2
Download BED file
Non redundant peaks MCM2
Download BED file
SEQUENCES MCM2
Download FASTA file
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Datasets Table for MCM2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MCM2 K-562 ENCODE Homo sapiens ENCSR552PSV 1,056
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.