MAFF

Information MAFF

Description

The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Full Name

MAF bZIP transcription factor F

Source NCBI

ReMap Statistics

Datasets
4
Biotypes
4
Peaks
187,218
Non-redundant peaks
123,831

TF Classification

Super Class
Basic domains
Class
Basic leucine zipper factors (bZIP)
Familly
Maf-related factors
Sub Familly
Small Maf factors

Source TFClass

External IDs

JASPAR
MA0495
Ensembl
ENSG00000185022
UniProt
Q9ULX9
Genevisible
Q9ULX9
RefSeq
NM_001161572
Aliases
U-MAF; hMafF
All peaks MAFF
Download BED file
Non redundant peaks MAFF
Download BED file
SEQUENCES MAFF
Download FASTA file
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Datasets Table for MAFF

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
MAFF GM12878 ENCODE Homo sapiens ENCSR237YZZ 6,053
MAFF Hep-G2 ENCODE Homo sapiens ENCSR000EEC 82,791
MAFF K-562 ENCODE Homo sapiens ENCSR000EGI 29,370
MAFF HeLa-S3 ENCODE Homo sapiens ENCSR140DSL 69,004
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.