MAF
Information MAF
- Description
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
- Full Name
MAF bZIP transcription factor
- Source NCBI
ReMap Statistics
- Datasets
- 6
- Biotypes
- 4
- Peaks
- 111,376
- Non-redundant peaks
- 81,942
TF Classification
- Super Class
- Basic domains
- Class
- Basic leucine zipper factors (bZIP)
- Familly
- Maf-related factors
- Sub Familly
- Large Maf factors
Source TFClass
External IDs
- JASPAR
- MA0501
- Ensembl
- ENSG00000178573
- UniProt
- O75444
- Genevisible
- O75444
- RefSeq
- NM_001031804
- Aliases
- AYGRP; CCA4; CTRCT21; c-MAF
Datasets Table for MAF
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| MAF | lymphocyte | Th17_IL10+_Day5 | GEO | Homo sapiens | GSE101389 | 12,353 | ||
| MAF | CD4 | TH1 | GEO | Homo sapiens | GSE72266 | 59,967 | ||
| MAF | CD4 | TH2 | GEO | Homo sapiens | GSE72266 | 31,386 | ||
| MAF | keratinocyte | epidermal_PROLIF | GEO | Homo sapiens | GSE52953 | 3,726 | ||
| MAF | monocyte | GEO | Homo sapiens | GSE98367 | 2,017 | |||
| MAF | monocyte | INFg | GEO | Homo sapiens | GSE98367 | 1,927 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |