KDM5B
Information KDM5B
- Description
This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
- Full Name
lysine demethylase 5B
- Source NCBI
ReMap Statistics
- Datasets
- 9
- Biotypes
- 8
- Peaks
- 393,555
- Non-redundant peaks
- 213,637
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- ARID domain factors
- Familly
- ARID-related factors
- Sub Familly
- JARID1
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000117139
- UniProt
- Q9UGL1
- Genevisible
- Q9UGL1
- RefSeq
- NM_001314042
- Aliases
- CT31; JARID1B; MRT65; PLU-1; PLU1; PPP1R98; PUT1; RBBP2H1A; RBP2-H1
Datasets Table for KDM5B
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| KDM5B | K-562 | ENCODE | Homo sapiens | ENCSR000AQA | 32,058 | |||
| KDM5B | WA01 | ENCODE | Homo sapiens | ENCSR000AUR | 1,826 | |||
| KDM5B | HCC2157 | GEO | Homo sapiens | GSE46055 | 59,819 | |||
| KDM5B | SUM159 | GEO | Homo sapiens | GSE46055 | 46,154 | |||
| KDM5B | SUM185 | GEO | Homo sapiens | GSE46055 | 16,029 | |||
| KDM5B | SUM185 | SHCTCF | GEO | Homo sapiens | GSE46055 | 56,311 | ||
| KDM5B | MCF-7 | GEO | Homo sapiens | GSE46055 | 21,541 | |||
| KDM5B | MDA-MB-231 | GEO | Homo sapiens | GSE46055 | 105,734 | |||
| KDM5B | T-47D | GEO | Homo sapiens | GSE46055 | 54,083 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |