KDM5A
Information KDM5A
- Description
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013]
- Full Name
lysine demethylase 5A
- Source NCBI
ReMap Statistics
- Datasets
- 5
- Biotypes
- 3
- Peaks
- 27,069
- Non-redundant peaks
- 12,462
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- ARID domain factors
- Familly
- ARID-related factors
- Sub Familly
- JARID1
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000073614
- UniProt
- P29375
- Genevisible
- P29375
- RefSeq
- NM_001042603
- Aliases
- RBBP-2; RBBP2; RBP2
Datasets Table for KDM5A
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| KDM5A | A-549 | ENCODE | Homo sapiens | ENCSR933MHJ | 5,282 | |||
| KDM5A | WA01 | ENCODE | Homo sapiens | ENCSR000AQL | 2,912 | |||
| KDM5A | WA01 | ENCODE | Homo sapiens | ENCSR160ZLP | 3,856 | |||
| KDM5A | T-47D | DMSO | GEO | Homo sapiens | GSE80593 | 6,679 | ||
| KDM5A | T-47D | MK2206 | GEO | Homo sapiens | GSE80593 | 8,340 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |