ISL1

Information ISL1

Description

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]

Full Name

ISL LIM homeobox 1

Source NCBI

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
55,428
Non-redundant peaks
55,428

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000016082
UniProt
P61371
Genevisible
P61371
RefSeq
NM_002202
Aliases
ISLET1; Isl-1
All peaks ISL1
Download BED file
Non redundant peaks ISL1
Download BED file
SEQUENCES ISL1
Download FASTA file
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Datasets Table for ISL1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
ISL1 SK-N-BE2-C GEO Homo sapiens GSE94822 55,428
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.