HNF1A
Information HNF1A
- Description
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
- Full Name
HNF1 homeobox A
- Source NCBI
ReMap Statistics
- Datasets
- 5
- Biotypes
- 4
- Peaks
- 141,956
- Non-redundant peaks
- 122,781
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- MA0114
- Ensembl
- ENSG00000135100
- UniProt
- P20823
- Genevisible
- P20823
- RefSeq
- NM_000545
- Aliases
- HNF-1A; HNF1; HNF4A; IDDM20; LFB1; MODY3; TCF-1; TCF1
Datasets Table for HNF1A
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| HNF1A | Hep-G2 | ENCODE | Homo sapiens | ENCSR800QIT | 15,205 | |||
| HNF1A | NY15 | GEO | Homo sapiens | GSE108150 | 8,115 | |||
| HNF1A | NY8 | GEO | Homo sapiens | GSE108150 | 93,580 | |||
| HNF1A | HEE | 1 | GEO | Homo sapiens | GSE76376 | 15,543 | ||
| HNF1A | HEE | 5 | GEO | Homo sapiens | GSE76376 | 9,513 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |