HDAC8
Information HDAC8
- Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Full Name
histone deacetylase 8
- Source NCBI
ReMap Statistics
- Datasets
- 2
- Biotypes
- 1
- Peaks
- 33,737
- Non-redundant peaks
- 30,238
TF Classification
- Super Class
- Unknown
- Class
- Unknown
- Familly
- Unknown
- Sub Familly
- Unknown
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000147099
- UniProt
- Q9BY41
- Genevisible
- Q9BY41
- RefSeq
- NM_001166418
- Aliases
- KDAC8
Datasets Table for HDAC8
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| HDAC8 | K-562 | ENCODE | Homo sapiens | ENCSR000DJZ | 10,170 | |||
| HDAC8 | K-562 | ENCODE | Homo sapiens | ENCSR835TCD | 23,567 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |