HDAC3
Information HDAC3
- Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
- Full Name
histone deacetylase 3
- Source NCBI
ReMap Statistics
- Datasets
- 3
- Biotypes
- 2
- Peaks
- 14,528
- Non-redundant peaks
- 12,507
TF Classification
- Super Class
- Unknown
- Class
- Unknown
- Familly
- Unknown
- Sub Familly
- Unknown
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000171720
- UniProt
- O15379
- Genevisible
- O15379
- RefSeq
- NM_001355039
- Aliases
- HD3; KDAC3; RPD3; RPD3-2
Datasets Table for HDAC3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| HDAC3 | K-562 | ENCODE | Homo sapiens | ENCSR024LKA | 5,002 | |||
| HDAC3 | VCaP | DHAT_2H | GEO | Homo sapiens | GSE28950 | 5,497 | ||
| HDAC3 | VCaP | ETOH | GEO | Homo sapiens | GSE28950 | 4,029 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |