HAND2

Information HAND2

Description

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. [provided by RefSeq, Jul 2008]

Full Name

heart and neural crest derivatives expressed 2

Source NCBI

ReMap Statistics

Datasets
3
Biotypes
3
Peaks
171,026
Non-redundant peaks
111,035

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000164107
UniProt
P61296
Genevisible
P61296
RefSeq
NM_021973
Aliases
DHAND2; Hed; Thing2; bHLHa26; dHand
All peaks HAND2
Download BED file
Non redundant peaks HAND2
Download BED file
SEQUENCES HAND2
Download FASTA file
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Datasets Table for HAND2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
HAND2 CLB-Ga GEO Homo sapiens GSE90683 57,260
HAND2 Kelly GEO Homo sapiens GSE94822 34,946
HAND2 SK-N-BE2-C GEO Homo sapiens GSE94822 78,820
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.