FUS

Information FUS

Description

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]

Full Name

FUS RNA binding protein

Source NCBI

ReMap Statistics

Datasets
2
Biotypes
2
Peaks
16,427
Non-redundant peaks
12,942

TF Classification

Super Class
NA
Class
NA
Familly
NA
Sub Familly
NA

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000089280
UniProt
P35637
Genevisible
P35637
RefSeq
NM_001170634
Aliases
ALS6; ETM4; FUS1; HNRNPP2; POMP75; TLS; hnRNP-P2
All peaks FUS
Download BED file
Non redundant peaks FUS
Download BED file
SEQUENCES FUS
Download FASTA file
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Datasets Table for FUS

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
FUS Hep-G2 ENCODE Homo sapiens ENCSR590QQP 11,497
FUS K-562 ENCODE Homo sapiens ENCSR051DXE 4,930
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.