FLI1
Information FLI1
- Description
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
- Full Name
Fli-1 proto-oncogene, ETS transcription factor
- Source NCBI
ReMap Statistics
- Datasets
- 22
- Biotypes
- 9
- Peaks
- 577,601
- Non-redundant peaks
- 254,728
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Tryptophan cluster factors
- Familly
- Ets-related factors
- Sub Familly
- Ets-like factors
Source TFClass
External IDs
- JASPAR
- MA0475
- Ensembl
- ENSG00000151702
- UniProt
- Q01543
- Genevisible
- Q01543
- RefSeq
- NM_001167681
- Aliases
- BDPLT21; EWSR2; SIC-1
Datasets Table for FLI1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| FLI1 | A-673 | 1_KRAB_eNKX2_1 | GEO | Homo sapiens | GSE106914 | 98,452 | ||
| FLI1 | A-673 | 1_KRAB_GFP | GEO | Homo sapiens | GSE106914 | 71,478 | ||
| FLI1 | A-673 | 2_KRAB_eSOX2_1 | GEO | Homo sapiens | GSE106914 | 52,563 | ||
| FLI1 | NB4 | GEO | Homo sapiens | GSE23730 | 17,464 | |||
| FLI1 | SKNO1 | GEO | Homo sapiens | GSE23730 | 56,585 | |||
| FLI1 | UAE | GEO | Homo sapiens | GSE23730 | 27,398 | |||
| FLI1 | UAE | ZINC | GEO | Homo sapiens | GSE23730 | 31,833 | ||
| FLI1 | A-673 | delta22_EWSFL-kd | GEO | Homo sapiens | GSE94480 | 125 | ||
| FLI1 | A-673 | Mut9_EWSFL-kd | GEO | Homo sapiens | GSE94480 | 908 | ||
| FLI1 | HUVEC-C | GEO | Homo sapiens | GSE109625 | 370 | |||
| FLI1 | HUVEC-C | VEGF_12h | GEO | Homo sapiens | GSE109625 | 5,750 | ||
| FLI1 | HUVEC-C | VEGF_1h | GEO | Homo sapiens | GSE109625 | 4,289 | ||
| FLI1 | HUVEC-C | VEGF_4h | GEO | Homo sapiens | GSE109625 | 1,174 | ||
| FLI1 | SK-N-MC | GEO | Homo sapiens | GSE61944 | 3,020 | |||
| FLI1 | SK-N-MC | SHFLI_48H | GEO | Homo sapiens | GSE61944 | 717 | ||
| FLI1 | SK-N-MC | SHFLI_96H | GEO | Homo sapiens | GSE61944 | 303 | ||
| FLI1 | SK-N-MC | SHGFP_48H | GEO | Homo sapiens | GSE61944 | 4,299 | ||
| FLI1 | SK-N-MC | SHGFP_96H | GEO | Homo sapiens | GSE61944 | 4,036 | ||
| FLI1 | TSU-1621MT | GEO | Homo sapiens | GSE60477 | 28,326 | |||
| FLI1 | ME-1 | GEO | Homo sapiens | GSE46044 | 12,366 | |||
| FLI1 | A-673-clone-Asp114 | GEO | Homo sapiens | GSE92738 | 138,055 | |||
| FLI1 | A-673 | GEO | Homo sapiens | GSE99959 | 18,090 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |