ETS1
Information ETS1
- Description
This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
- Full Name
ETS proto-oncogene 1, transcription factor
- Source NCBI
ReMap Statistics
- Datasets
- 25
- Biotypes
- 13
- Peaks
- 537,522
- Non-redundant peaks
- 148,952
TF Classification
- Super Class
- Helix-turn-helix domains
- Class
- Tryptophan cluster factors
- Familly
- Ets-related factors
- Sub Familly
- Ets-like factors
Source TFClass
External IDs
- JASPAR
- MA0098
- Ensembl
- ENSG00000134954
- UniProt
- P14921
- Genevisible
- P14921
- RefSeq
- NM_001143820
- Aliases
- ETS-1; EWSR2; FLJ10768; c-ets-1; p54
Datasets Table for ETS1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| ETS1 | GM12878 | ENCODE | Homo sapiens | ENCSR000BKA | 9,524 | |||
| ETS1 | hESC | ENCODE | Homo sapiens | ENCSR534VHI | 13,523 | |||
| ETS1 | ALL-SIL | GEO | Homo sapiens | GSE102209 | 2,123 | |||
| ETS1 | A-549 | ENCODE | Homo sapiens | ENCSR000BPU | 18,564 | |||
| ETS1 | Hep-G2 | ENCODE | Homo sapiens | ENCSR681WHQ | 22,000 | |||
| ETS1 | K-562 | ENCODE | Homo sapiens | ENCSR000BKQ | 28,436 | |||
| ETS1 | OVCAR-8 | GEO | Homo sapiens | GSE101832 | 14,307 | |||
| ETS1 | HEY-A8 | GEO | Homo sapiens | GSE101832 | 13,671 | |||
| ETS1 | DU145 | GEO | Homo sapiens | GSE59021 | 9,069 | |||
| ETS1 | 786-O | GEO | Homo sapiens | GSE86092 | 32,141 | |||
| ETS1 | HUVEC-C | GEO | Homo sapiens | GSE109625 | 15,849 | |||
| ETS1 | HUVEC-C | VEGF_12h | GEO | Homo sapiens | GSE109625 | 39,675 | ||
| ETS1 | HUVEC-C | VEGF_1h | GEO | Homo sapiens | GSE109625 | 16,135 | ||
| ETS1 | HUVEC-C | VEGF_4h | GEO | Homo sapiens | GSE109625 | 32,400 | ||
| ETS1 | HUVEC-C | GEO | Homo sapiens | GSE41166 | 25,378 | |||
| ETS1 | HUVEC-C | VEGF_12H | GEO | Homo sapiens | GSE41166 | 56,821 | ||
| ETS1 | HUVEC-C | VEGF_1H | GEO | Homo sapiens | GSE41166 | 25,129 | ||
| ETS1 | HUVEC-C | VEGF_4H | GEO | Homo sapiens | GSE41166 | 50,035 | ||
| ETS1 | HUVEC-C | GEO | Homo sapiens | GSE93030 | 15,837 | |||
| ETS1 | HUVEC-C | 12h | GEO | Homo sapiens | GSE93030 | 39,641 | ||
| ETS1 | HUVEC-C | 1h | GEO | Homo sapiens | GSE93030 | 16,124 | ||
| ETS1 | HUVEC-C | 4h | GEO | Homo sapiens | GSE93030 | 32,395 | ||
| ETS1 | HUVEC-C | modETS1 | GEO | Homo sapiens | GSE93030 | 3,045 | ||
| ETS1 | PANC-1 | GEO | Homo sapiens | GSE59021 | 5,365 | |||
| ETS1 | RWPE-1 | GEO | Homo sapiens | GSE29808 | 335 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |