EP300

Description: This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
Full Name: E1A binding protein p300; Source NCBI

All peaks EP300

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Non redundant peaks EP300

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SEQUENCES EP300

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Target name	Target modification	Ecotype/Strain	Biotype	Biotype modification	Source	Species	Experiment	Peaks
EP300			GM12878		ENCODE	Homo sapiens	ENCSR000BHB	9,864
EP300			GM12878		ENCODE	Homo sapiens	ENCSR000DZD	5,603
EP300			GM12878		ENCODE	Homo sapiens	ENCSR000DZG	6,680
EP300			Ishikawa		ENCODE	Homo sapiens	ENCSR000BUE	37,031
EP300			neural		ENCODE	Homo sapiens	ENCSR843ZUP	48,009
EP300			osteoblast		ENCODE	Homo sapiens	ENCSR000AUD	20,358
EP300			A-549		ENCODE	Homo sapiens	ENCSR000BPW	34,851
EP300			Hep-G2		ENCODE	Homo sapiens	ENCSR000BLW	55,105
EP300			Hep-G2		ENCODE	Homo sapiens	ENCSR000EDV	18,081
EP300			K-562		ENCODE	Homo sapiens	ENCSR000AQB	184
EP300			K-562		ENCODE	Homo sapiens	ENCSR000EGE	41,233
EP300			K-562		ENCODE	Homo sapiens	ENCSR000EGY	3,222
EP300			MCF-7		ENCODE	Homo sapiens	ENCSR000BTR	15,788
EP300			SK-N-SH		ENCODE	Homo sapiens	ENCSR000BUA	42,819
EP300			SK-N-SH		ENCODE	Homo sapiens	ENCSR000EHV	42,843
EP300			T-47D		ENCODE	Homo sapiens	ENCSR000BLM	26,656
EP300			WA01		ENCODE	Homo sapiens	ENCSR000AUQ	9,125
EP300			WA01		ENCODE	Homo sapiens	ENCSR000BKK	19,843
EP300			HeLa-S3		ENCODE	Homo sapiens	ENCSR000ECV	33,577
EP300			HeLa-S3		ENCODE	Homo sapiens	ENCSR680OFU	46,662
EP300			hESC		GEO	Homo sapiens	GSE17917	2,836
EP300			MCF-7	DMSO	GEO	Homo sapiens	GSE29073	2,463
EP300			MCF-7	E2	GEO	Homo sapiens	GSE29073	2,291
Target name	Target modification	Ecotype/Strain	Biotype	Biotype modification	Source	Species	Experiment	Peaks