CTCFL
Information CTCFL
- Description
CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
- Full Name
CCCTC-binding factor like
- Source NCBI
ReMap Statistics
- Datasets
- 5
- Biotypes
- 4
- Peaks
- 107,785
- Non-redundant peaks
- 63,623
TF Classification
- Super Class
- Zinc-coordinating DNA-binding domains
- Class
- C2H2 zinc finger factors
- Familly
- More than 3 adjacent zinc finger factors
- Sub Familly
- CTCF-like factors
Source TFClass
External IDs
- JASPAR
- MA1102
- Ensembl
- ENSG00000124092
- UniProt
- Q8NI51
- Genevisible
- Q8NI51
- RefSeq
- NM_001269040
- Aliases
- BORIS; CT27; dJ579F20.2
Datasets Table for CTCFL
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| CTCFL | K-562 | ENCODE | Homo sapiens | ENCSR000BNK | 26,328 | |||
| CTCFL | NHDF | GEO | Homo sapiens | GSE70764 | 9 | |||
| CTCFL | delta-47 | GEO | Homo sapiens | GSE70764 | 15,015 | |||
| CTCFL | K-562 | GEO | Homo sapiens | GSE70764 | 31,986 | |||
| CTCFL | OVCAR-8 | GEO | Homo sapiens | GSE70764 | 34,447 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |