CRY2

Information CRY2

Description

Blue light receptor mediating blue-light regulated cotyledon expansion and flowering time. Positive regulator of the flowering-time gene CONSTANS. This gene possesses a light-induced CNT2 N-terminal homodimerisation domain.Involved in blue-light induced stomatal opening. Involved in triggering chromatin decondensation. An 80-residue motif (NC80) is sufficient to confer CRY2's physiological function. It is proposed that the PHR domain and the C-terminal tail of the unphosphorylated CRY2 form a ''closed'' conformation to suppress the NC80 motif in the absence of light. In response to blue light, the C-terminal tail of CRY2 is phosphorylated and electrostatically repelled from the surface of the PHR domain to form an ''open'' conformation, resulting in derepression of the NC80 motif and signal transduction to trigger photomorphogenic responses. Cry2 phosphorylation and degradation both occur in the nucleus.

Full Name

cryptochrome 2

Source NCBI

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
2,572
Non-redundant peaks
2,572

TF Classification

Familly
REM
Sub Familly
NA

Source AtTFDB

External IDs

JASPAR
Ensembl
AT1G04400
UniProt
Q96524
Genevisible
Q96524
RefSeq
NM_179257.2
Aliases
All peaks CRY2
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Non redundant peaks CRY2
Download BED file
SEQUENCES CRY2
Download FASTA file
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Datasets Table for CRY2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CRY2 Col-0 Col-0_seedling 5d GEO Arabidopsis thaliana GSE68193 2,572
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

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The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.