CRY1
Information CRY1
- Description
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
- Full Name
cryptochrome circadian regulator 1
- Source NCBI
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 23,589
- Non-redundant peaks
- 23,589
TF Classification
- Super Class
- Unknown
- Class
- Unknown
- Familly
- Unknown
- Sub Familly
- Unknown
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000008405
- UniProt
- Q16526
- Genevisible
- Q16526
- RefSeq
- NM_004075
- Aliases
- DSPD; PHLL1