CREB1

Information CREB1

Description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Full Name

cAMP responsive element binding protein 1

Source NCBI

ReMap Statistics

Datasets
22
Biotypes
11
Peaks
740,980
Non-redundant peaks
310,990

TF Classification

Super Class
Basic domains
Class
Basic leucine zipper factors (bZIP)
Familly
CREB-related factors
Sub Familly
CREB-like factors

Source TFClass

External IDs

JASPAR
MA0018
Ensembl
ENSG00000118260
UniProt
P16220
Genevisible
P16220
RefSeq
NM_001320793
Aliases
CREB; CREB-1
All peaks CREB1
Download BED file
Non redundant peaks CREB1
Download BED file
SEQUENCES CREB1
Download FASTA file
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Datasets Table for CREB1

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CREB1 GM12878 ENCODE Homo sapiens ENCSR000BUF 41,629
CREB1 Ishikawa ENCODE Homo sapiens ENCSR000BUR 6,870
CREB1 A-549 ENCODE Homo sapiens ENCSR000BRA 7,553
CREB1 A-549 ENCODE Homo sapiens ENCSR000BRB 52,350
CREB1 A-549 ENCODE Homo sapiens ENCSR000BRC 21,795
CREB1 Hep-G2 ENCODE Homo sapiens ENCSR000BVL 31,800
CREB1 Hep-G2 ENCODE Homo sapiens ENCSR112ALD 60,266
CREB1 Hep-G2 ENCODE Homo sapiens ENCSR331ORD 5,810
CREB1 K-562 ENCODE Homo sapiens ENCSR000BSO 24,568
CREB1 MCF-7 ENCODE Homo sapiens ENCSR620DUQ 76,716
CREB1 MCF-7 ENCODE Homo sapiens ENCSR897JAS 78,357
CREB1 WA01 ENCODE Homo sapiens ENCSR000BSN 50,535
CREB1 MDA-MB-134 GEO Homo sapiens GSE109103 15,061
CREB1 MDA-MB-134 E2 GEO Homo sapiens GSE109103 2,215
CREB1 MDA-MB-134 FI GEO Homo sapiens GSE109103 13,668
CREB1 LNCaP GEO Homo sapiens GSE63034 25,293
CREB1 Hep-G2 GEO Homo sapiens GSE72082 81,929
CREB1 KG-1 DMSO GEO Homo sapiens GSE74928 481
CREB1 KG-1 XX65023 GEO Homo sapiens GSE74928 5,378
CREB1 LNCaP-abl GEO Homo sapiens GSE63034 27,249
CREB1 LNCaP-abl SHCTR GEO Homo sapiens GSE63034 52,281
CREB1 LNCaP-abl SHFOXA1 GEO Homo sapiens GSE63034 59,176
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.