CDK7

Information CDK7

Description

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]

Full Name

cyclin dependent kinase 7

Source NCBI

ReMap Statistics

Datasets
6
Biotypes
3
Peaks
93,107
Non-redundant peaks
51,935

TF Classification

Super Class
Unknown
Class
Unknown
Familly
Unknown
Sub Familly
Unknown

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000277273
UniProt
P50613
Genevisible
P50613
RefSeq
NM_001324069
Aliases
CAK; CAK1; CDKN7; HCAK; MO15; STK1; p39MO15
All peaks CDK7
Download BED file
Non redundant peaks CDK7
Download BED file
SEQUENCES CDK7
Download FASTA file
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Datasets Table for CDK7

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CDK7 Jurkat GEO Homo sapiens GSE50622 15,933
CDK7 Jurkat DMSO GEO Homo sapiens GSE60027 23,501
CDK7 Jurkat THZ2102 GEO Homo sapiens GSE60027 11,002
CDK7 Jurkat GEO Homo sapiens GSE83777 32,533
CDK7 SK-MEL-147 GEO Homo sapiens GSE45984 8,955
CDK7 MM1-S GEO Homo sapiens GSE45984 1,183
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.