CBX2

Information CBX2

Description

This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010]

Full Name

chromobox 2

Source NCBI

ReMap Statistics

Datasets
2
Biotypes
2
Peaks
47,972
Non-redundant peaks
47,765

TF Classification

Super Class
Unknown
Class
Unknown
Familly
Unknown
Sub Familly
Unknown

Source TFClass

External IDs

JASPAR
Ensembl
ENSG00000173894
UniProt
Q14781
Genevisible
Q14781
RefSeq
NM_005189
Aliases
MGC10561
All peaks CBX2
Download BED file
Non redundant peaks CBX2
Download BED file
SEQUENCES CBX2
Download FASTA file
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Datasets Table for CBX2

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
CBX2 K-562 ENCODE Homo sapiens ENCSR000ATU 33,869
CBX2 HEK293T GEO Homo sapiens GSE34774 14,103
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

You are using the 2020 ReMap (3rd) release.
The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.