CBFA2T3
Information CBFA2T3
- Description
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
- Full Name
CBFA2/RUNX1 partner transcriptional co-repressor 3
- Source NCBI
ReMap Statistics
- Datasets
- 1
- Biotypes
- 1
- Peaks
- 55,031
- Non-redundant peaks
- 55,031
TF Classification
- Super Class
- NA
- Class
- NA
- Familly
- NA
- Sub Familly
- NA
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000129993
- UniProt
- O75081
- Genevisible
- O75081
- RefSeq
- NM_005187
- Aliases
- ETO2; MTG16; MTGR2; RUNX1T3; ZMYND4
Datasets Table for CBFA2T3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| CBFA2T3 | K-562 | ENCODE | Homo sapiens | ENCSR697YLJ | 55,031 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |