BZIP28

Information BZIP28

Description

Encodes bZIP28, a putative membrane-tethered transcriptional factor. Up-regulated in response to heat; a bZIP28 null mutant has a heat-sensitive phenotype. bZIP28 has a similar domain structure to the mammalian ATF6 protein involved in the unfolded protein response (UPR), and shares a bZIP domain, transmembrane domain, and a canonical S1P cleavage site. The bZIP28 seems to be glycosylated in vivo. bZIP28 does not appear to be transcriptionally up-regulated by UPR-inducing tunicamycin (TM) treatment. But, the expression level of three UPR-related genes is reduced in TM-treated zip28 mutants relative to wild type seedlings. And several UPR genes are transcriptionally upregulated when an N-terminal portion of the bZIP28 protein is expressed using the 35S promoter. A myc:bZIP28 fusion protein appears to be cleaved, likely at a canonical S2 cleavage site, following a TM treatment or a DTT stress-inducing treatment, but not a salt treatment. A portion of the mGFP:bZIP28 protein present in root cells appears to translocate from the cytoplasm and ER to the nucleus following TM treatment.

Full Name

Basic-leucine zipper (bZIP) transcription factor family protein

Source NCBI

ReMap Statistics

Datasets
1
Biotypes
1
Peaks
817
Non-redundant peaks
817

TF Classification

Familly
bZIP
Sub Familly
bZIP family transcription factor

Source AtTFDB

External IDs

JASPAR
Ensembl
AT3G10800
UniProt
Q9SG86
Genevisible
Q9SG86
RefSeq
NM_111917.5
Aliases
All peaks BZIP28
Download BED file
Non redundant peaks BZIP28
Download BED file
SEQUENCES BZIP28
Download FASTA file
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Datasets Table for BZIP28

Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks
BZIP28 Col-0 Col-0_leaves tnt_col GEO Arabidopsis thaliana GSE60141 817
Target name Target modification Ecotype/Strain Biotype Biotype modification Source Species Experiment Peaks

ReMap is a database of transcriptional regulators peaks derived from curated ChIP-seq, ChIP-exo, DAP-seq experiments in Human and Thaliana.

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The ReMap catalogues (2020, 2018, 2015) are under CC BY-NC 4.0 international license, while ReMapEnrich, remap-pipeline under GNU GPLv3 licence.

Inserm TAGC
AMU AMU-MESO

This work was granted access to the HPC resources of Aix-Marseille Université financed by the project Equip@Meso (ANR-10-EQPX-29-01) of the program "Investissements d’Avenir" supervised by the Agence Nationale de la Recherche.