BMI1
Information BMI1
- Description
This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015]
- Full Name
BMI1 proto-oncogene, polycomb ring finger
- Source NCBI
ReMap Statistics
- Datasets
- 5
- Biotypes
- 5
- Peaks
- 38,030
- Non-redundant peaks
- 32,868
TF Classification
- Super Class
- Unknown
- Class
- Unknown
- Familly
- Unknown
- Sub Familly
- Unknown
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000168283
- UniProt
- P35226
- Genevisible
- P35226
- RefSeq
- NM_005180
- Aliases
- FLVI2/BMI1; PCGF4; RNF51; flvi-2/bmi-1
Datasets Table for BMI1
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| BMI1 | GM12878 | ENCODE | Homo sapiens | ENCSR469WII | 12,987 | |||
| BMI1 | K-562 | ENCODE | Homo sapiens | ENCSR782WRO | 10,383 | |||
| BMI1 | MCF-7 | ENCODE | Homo sapiens | ENCSR966YYJ | 14,461 | |||
| BMI1 | HEK293T | GEO | Homo sapiens | GSE34774 | 55 | |||
| BMI1 | LNCaP-C4-2 | GEO | Homo sapiens | GSE97831 | 144 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |