BCL3
Information BCL3
- Description
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]
- Full Name
BCL3 transcription coactivator
- Source NCBI
ReMap Statistics
- Datasets
- 2
- Biotypes
- 2
- Peaks
- 76,324
- Non-redundant peaks
- 72,288
TF Classification
- Super Class
- Immunoglobulin fold
- Class
- Rel homology region (RHR) factors
- Familly
- Ankyrin domain-only factors
- Sub Familly
- IkappaB-related factors
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000069399
- UniProt
- P20749
- Genevisible
- P20749
- RefSeq
- NM_005178
- Aliases
- BCL4; D19S37
Datasets Table for BCL3
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| BCL3 | GM12878 | ENCODE | Homo sapiens | ENCSR000BNQ | 37,840 | |||
| BCL3 | A-549 | ENCODE | Homo sapiens | ENCSR000BQH | 38,484 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |