AHR
Information AHR
- Description
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]
- Full Name
aryl hydrocarbon receptor
- Source NCBI
ReMap Statistics
- Datasets
- 8
- Biotypes
- 3
- Peaks
- 567,764
- Non-redundant peaks
- 462,961
TF Classification
- Super Class
- Basic domains
- Class
- Basic helix-loop-helix factors (bHLH)
- Familly
- PAS domain factors
- Sub Familly
- Ahr-like factors
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000106546
- UniProt
- P35869
- Genevisible
- P35869
- RefSeq
- NM_001621
- Aliases
- RP85; bHLHe76
Datasets Table for AHR
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| AHR | Hep-G2 | ENCODE | Homo sapiens | ENCSR412ZDC | 211,391 | |||
| AHR | GM01310 | 3MC | GEO | Homo sapiens | GSE116632 | 25,821 | ||
| AHR | GM01310 | DMSO | GEO | Homo sapiens | GSE116632 | 27,145 | ||
| AHR | MCF-7 | GEO | Homo sapiens | GSE41820 | 194,004 | |||
| AHR | MCF-7 | DMSO_1d | GEO | Homo sapiens | GSE90550 | 9,903 | ||
| AHR | MCF-7 | DMSO_45min | GEO | Homo sapiens | GSE90550 | 29,405 | ||
| AHR | MCF-7 | TCDD_1d | GEO | Homo sapiens | GSE90550 | 10,714 | ||
| AHR | MCF-7 | TCDD_45min | GEO | Homo sapiens | GSE90550 | 59,381 | ||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |