AFF4
Information AFF4
- Description
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]
- Full Name
AF4/FMR2 family member 4
- Source NCBI
ReMap Statistics
- Datasets
- 10
- Biotypes
- 4
- Peaks
- 210,856
- Non-redundant peaks
- 97,628
TF Classification
- Super Class
- Unknown
- Class
- Unknown
- Familly
- Unknown
- Sub Familly
- Unknown
Source TFClass
External IDs
- JASPAR
- Ensembl
- ENSG00000072364
- UniProt
- Q9UHB7
- Genevisible
- Q9UHB7
- RefSeq
- NM_014423
- Aliases
- AF5Q31; CHOPS; MCEF
Datasets Table for AFF4
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |
|---|---|---|---|---|---|---|---|---|
| AFF4 | CD4 | TH1_BAY | GEO | Homo sapiens | GSE62482 | 11,253 | ||
| AFF4 | CD4 | TH1_DMSO | GEO | Homo sapiens | GSE62482 | 18,520 | ||
| AFF4 | HEK293T | GEO | Homo sapiens | GSE34097 | 266 | |||
| AFF4 | HeLa | GEO | Homo sapiens | GSE40632 | 40,361 | |||
| AFF4 | HeLa | DOX | GEO | Homo sapiens | GSE40632 | 48,199 | ||
| AFF4 | HeLa | DOX_EGF | GEO | Homo sapiens | GSE40632 | 46,285 | ||
| AFF4 | HeLa | EGF | GEO | Homo sapiens | GSE40632 | 42,387 | ||
| AFF4 | HCT-116 | SERUM | GEO | Homo sapiens | GSE30267 | 1,102 | ||
| AFF4 | HCT-116 | STARVED | GEO | Homo sapiens | GSE30267 | 394 | ||
| AFF4 | HCT-116 | GEO | Homo sapiens | GSE47938 | 2,089 | |||
| Target name | Target modification | Ecotype/Strain | Biotype | Biotype modification | Source | Species | Experiment | Peaks |